Ashman’s phenomenon is a special type of aberrant ventricular conduction, in which a bundle branch block occurs as a result of an abrupt change in the length of the cardiac cycle. Ultimately the functional and anatomical structure of the atria becomes so remodeled that the atrial fibrillation becomes permanent. Although ablation therapy is a proven effective method, there is always a risk of future relapse. Most individuals, however, do experience symptoms and they do so before developing complications. Atrial fibrillation is a condition that disrupts your heartbeat. ", Dr. Wilber Su,Cavanaugh Heart Center, Phoenix, AZ, "...masterful. Interpreting a ECG strip involves counting the squares of the tracing. Rhythm control means attempting to restore sinus rhythm. and patients typically report that the palpitations started suddenly. Video: Cardiac Conduction System and its Relationship with ECG. A dedicated ECG machine would usually print onto graph paper which has a background pattern of 1mm squares (often in red or green), with bold divisions every 5 mm in both vertical and horizontal directions. The output of an ECG recorder is a graph (or sometimes several graphs, representing each of the leads) with time represented on the x-axis and voltage represented on the y-axis. Although atrial fibrillation is trigger by an ectopic focus in most cases, it may also be triggered by other arrhythmias such as AVRT or atrial flutter or even bradycardia. Atrial Fibrillation with a ventricular response in excess of 100 bpm is commonly referred to as Atrial Fibrillation with “rapid ventricular response” or "uncontrolled A-fib". Atrial Fibrillation: Resources for Patients (www.A-Fib.com)?Empowering patients to seek their A-Fib cure. A large body of evidence demonstrate that atrial fibrillation in itself causes hemodynamic and electrophysiological changes in the myocardium which lead to increased susceptibility to new episodes of atrial fibrillation. Atrial fibrillation is typically a progressive disease that usually evolves towards permanent atrial fibrillation. Rhythm control may be considered although most patients will relapse within one year and it does not provide a survival benefit as compared with rate control. The following blood samples should be analysed: hemoglobin, sodium, potassium, creatinine, calcium, liver enzymes, lipids, glucose, HbA1c, thyroid stimulating hormone and T4. In the case of Atrial Fibrillation, the consistent P waves are replaced by fibrillatory waves, which vary in amplitude, shape, and timing (compare the two illustrations below). The normal duration (interval) of the QRS complex is between 0.08 and 0.10 seconds. Cardioversion is contraindicated after 48 hours due to high risk of thromboembolism (unless a transesophageal echocardiogram can be performed to rule out thrombus formation in the atria (left atrial appendage). Healthy hearts contract in a synchronized way. Atrial fibrillation (AFib) is a heart condition that affects your heart’s rhythm and output and can cause stroke. • Schematic diagram of normal sinus rhythm for a human heart as seen on ECG (with English labels). The EKG rhythm will appear irregular. The latter (bradycardia) is believed to cause atrial fibrillation because at low heart rates ectopic focuses may come to express themselves when they are not suppressed by the sinoatrial node. In any instance, in any arrhythmia, it is always more safe to use electrical cardioversion than trying anything else. AFib is a heart disease that causes the atria of the heart to have a conduction or electrical problem that results in a chaotic, irregular production of irregular QRS waves with no P waves. Try these curated collections. The patients age, active medications and concomitant AV-blocks modify the ventricular rate. You can detect these medical-grade assessments from any place or any time, as long as you have your device on you. Sometimes atrial fibrillation results in a course atrial flutter wave on the ECG, but the baseline can also be flat. “I really appreciate all the information on your website as it allows me to be a better informed patient and to know what questions to ask my EP. In multivariable models (i.e statistical models in which adjustment has been made for confounders) individuals with atrial fibrillation are at five times increased risk of stroke and two times increased mortality, as compared with individuals without atrial fibrillation. Atrial fibrillation consists of the appearance of disorganized stimuli at atria, with rates from 350 to 600 bpm. However, electrical and pharmacological cardioversion does limit the natural duration of the arrhythmia and may therefore affect the classification. The next slight rising section, the T wave, measures the resting period of the ventricles. Disclaimer: the authors of this Web site are not medical doctors and are not affiliated with any medical school or organization. Ablation therapy should be considered in all patients with symptomatic atrial fibrillation which is paroxysmal or persistent. Randomized controlled trials have not demonstrated any clear difference in mortality when comparing rate and rhythm control. The overall prevalence in a Western population is 1.0% to 1.5%. What is atrial fibrillation? Irregularly irregular rhythm. Atrial fibrillation is recognized on ECG by the absence of P waves and presence of fibrillary waves. Approximately 60% of cases of acute atrial fibrillation will convert spontaneously to sinus rhythm within 16 hours from onset of symptoms. Atrial rhythm, atrial tachycardia and multifocal atrial tachycardia, Sinus tachycardia (ST), Inappropriate Sinus tachycardia (IST) and Sinoatrial Node Reentry Tachycardia (SANRT), Management and diagnosis of tachycardias (narrow complex tachycardia and wide complex tachycardia). The hallmark of atrial fibrillation is absence of P-waves and an irregularly irregular (i.e totally irregular) ventricular rate. Such thrombi may leave the appendage and enter the systemic circulation which causes thromboembolic occlusions of arteries in the brain, limbs or other organs. ecg atrial fibrillation heart fibrilation fibrillation atrial fibrillation ecg abnormal heart rhythm heart anatomical ecg cardiology, heart doctor red cardiovascular medicine abnormal heart. Click on image to go to the video page. The ventricular rate is completely irregular, typically in the range of 100 to 180 beats per minute. Or you might … Atrial Fibrillation or afib may or may not cause symptoms. Wikimedia Common, Public Domain. heart rhythm disorder that causes a rapid and irregular heartbeat This type of atrial fibrillation has a good prognosis and generally do not require anticoagulation therapy. However, rhythm control conveys risks (most antiarrhythmic drugs have a pro-arrhythmic effect as well), which is why clinicians mostly choose rate control. Individuals with pre-excitation (Wolff-Parkinson-White syndrome) are at high risk of developing atrial fibrillation. A recent meta-analysis by Ganesan et al (European Heart Journal (2016) 37, 1591-1602) showed that paroxysmal atrial fibrillation is associated with a  lower risk of stroke than persistent atrial fibrillation. A flat baseline is more often seen in long standing atrial fibrillation. Misdiagnosis of atrial fibrillation carries significant implications for patients. A glitch in the heart’s … If your doctor thinks you have it, the first thing they’ll do is listen to your heart. The baseline (isoelectric line between QRS complexes) is characterized by either fibrillatory waves (f-waves) or just minute oscillations. This results in the inability of the heart to contract. Ablation is a highly effective treatment for paroxysmal atrial fibrillation. Last accessed April 13, 2014, URL: http://commons.wikimedia.org/wiki/File%3ASinusRhythmLabels.svg, • Diagram of electrocardiogram paper. New impulse waves will spread from the re-entry and these waves may collide with other impulse waves and either be terminated or encounter new blocks which fragment the impulse. Rate control does not affect the rhythm per se. Fibrillation of the atria may result in … Prevalence of atrial fibrillation correlates strongly with age. Electrical cardioversion is the most effective method, yielding a success rate of >90% with biphasic shock ≥200 J. Pharmacological cardioversion (flecainide, propafenon, ibutilid, amiodarone, vernakalant) are less effective (approximately 75% success rate) and these antiarrhythmic drugs may actually cause arrhythmias as well as circulatory compromise due to negative inotropic effect. Doctors & patients are saying about 'Beat Your A-Fib'... "If I had [your book] 10 years ago, it would have saved me 8 years of hell.”, Roy Salmon, Patient, A-Fib Free, Adelaide, Australia, "This book is incredibly complete and easy-to-understand for anybody. Get a full year access for only $26! Echocardiography should be performed in virtually all cases of newly diagnosed atrial fibrillation. The terms valvular and non-valvular atrial fibrillation are used to indicate whether the atrial fibrillation might be secondary to valvular disease. This is generally a cure for atrial fibrillation, because elimination of the trigger will remove the initial cause. Your doctor may order several tests to diagnose your condition, including: 1. For those not interested in electrocardiology, it is sufficient to know that atrial fibrillation is caused by an electrical chaos in the atria. Refer to ECG in Figure 3. Welcome to our atrial fibrillation reference page. Once atrial fibrillation is confirmed or suspected your doctor will perform further tests to check your heart muscle and heart valves and to screen for blood clots. In atrial flutter, there is a “sawtooth” pattern on an ECG. Nothing contained in this service is intended to be for medical diagnosis or treatment. Moreover, certain other tachyarrhythmias predispose to developing atrial fibrillation: atrial flutter, AVNRT and AVRT (pre-excitation, WPW syndrome) being the most common. This will confirm the diagnosis of atrial fibrillation and rule out other conditions. Some studies suggest that up to 30% of patients with clinically overt pre-excitation develop atrial fibrillation. It may also start as other forms of arrhythmia such as atrial flutter that then transform into AF. In such cases, absence of P waves and a totally irregular RR interval will give the clue to the presence of underlying atrial fibrillation. A-Fib.com top rated by Healthline.com since 2014. Common symptoms of AFib are weakness, dizziness, anxiety, and shortness of breath. This page provides a definition followed by an synopsis of EKG features. An ECG uses small sensors (electrodes) attached to your chest and arms to sense and record electrical signals as they travel through your heart. Us What You think | Press Room | GuideStar Seal | HON certification | Disclosures | Terms of Use | Privacy Policy, Click to share on Facebook (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Pinterest (Opens in new window), Click to share on Tumblr (Opens in new window), Click to share on Reddit (Opens in new window), Click to share on Pocket (Opens in new window), A-Fib.com top rated by Healthline.com since, Do-It-Yourself ECG: A Review of Consumer Handheld ECG Monitors, The CHADS2 & CHA2DS-VASc Stroke-Risk Grading Systems, Instructional A-Fib Videos and Animations, Creative Commons Attribution-ShareAlike 4.0 International License. Fortunately, the treatment of atrial fibrillation has come a long way. Sometimes fibrillary waves may be quite fine so as to be almost unrecognizable in certain leads. The explanation for the fact that the number of ectopic foci and re-entry circuits increase is because the atrial fibrillation (and the risk factors accompanying it) induce electrophysiological and anatomical changes in the atria and these changes promote triggers and drivers. Your doctor will diagnose atrial fibrillation on an electrocardiogram (EKG). What you do to help people through this [A-Fib] process is really incredible.". The trigger is composed of an ectopic focus which discharges impulses at high rate. Atrial fibrillation is the most common pathologic tachyarrhythmia (only sinus tachycardia is more common). If there are no signs of circulatory compromise one may expect the situation for 48 hours (counting from symptom onset) until cardioversion is attempted. Large f-waves must not be mistaken for flutter waves (F-waves) which are seen in atrial flutter. Sotalol is reserved for cardiologists, as it has pro-arrhythmic effects as well. Atrial fibrillation: definitions, causes, risk factors, ECG diagnosis and management. Atrial fibrillation with very rapid ventricular rate may appear as a regular rhythm (which is yet another reason to switch from 25 mm/s to 50 mm/s paper speed), which is why it is important to carefully measure the regularity of the rhythm. Rate control is accomplished with medications that affect the AV node; more specifically these drugs slow conduction through the AV node and this results in fewer atrial impulses being conducted to the ventricles. ECG recording of normal heart rhythm. Prevalence of atrial fibrillation correlates strongly with age. In such individuals, screening with ECG may reveal atrial fibrillation. The risk of thromboembolism is not, as previously believed, equal in all forms of atrial fibrillation. this gradual evolution of atrial myocardium is referred to as atrial remodeling. This is not surprising given the adverse effects of long periods of tachycardia and desynchronized atrial and ventricular activity. Absence of an isoelectric baseline. It is generally not meaningful trying to cardiovert valvular atrial fibrillation as the vast majority wMeill relapse to atrial fibrillation shortly after cardioversion, if it succeeds at all. In AFib, the ECG test shows an irregular ventricular rate. Aging, the strongest risk factor of atrial fibrillation, leads to degeneration of the myocardium and conduction cells. All clinically relevant aspects of atrial fibrillation – from risk factors, complications, electrophysiological mechanisms, ECG interpretation to management – are discussed in this chapter. Next. Doctors & patients are saying about 'A-Fib.com'... "A-Fib.com is a great web site for patients, that is unequaled by anything else out there. Always seek the advice of your physician or other qualified health professional prior to starting any new treatment or with any questions you may have regarding a medical condition. Join our newsletter and get our free ECG Pocket Guide! Electrocardiogram (ECG). Details on medications and dosages follow in Table 1. These impulse waves collide with each other and with refractory cells, which fragments the waves and causes additional chaos. How would you know to suspect it? ", Ira David Levin, heart patient, Rome, Italy, "Within the pages of Beat Your A-Fib, Dr. Steve Ryan, PhD, provides a comprehensive guide for persons seeking to find a cure for their Atrial Fibrillation. These impulses may induce short bursts of atrial fibrillation but unless a driver is established, the fibrillation will cease once the trigger stops discharging impulses. Atrial flutter: from ECG to clinical management. This heart tracing shows a distinct pattern in the electricity of the heart that your doctor can diagnose. The information on this site is not intended nor implied to be a substitute for professional medical advice. The autonomic nervous system appears to have an important role in inducing paroxysmal atrial fibrillation. 12 Nov 2020 • Jiacheng Wang • Weiheng Li. Atrial fibrillation debuting with congestive heart failure is uncommon among persons with previously normal left ventricular function. You managed to combine an encyclopedic compilation of information with the simplicity of presentation that enhances the delivery of the information to the reader. Atrial Fibrillation Lesson. Rate control implies the use of medications that slow ventricular rate (beta-blockers being the mainstay of this therapy). QRS complexes usually < 120 ms unless pre-existing bundle branch block, accessory pathway, or rate related aberrant conduction. The ECG signal strip is a graphic tracing of the electrical activity of the heart. The incidence is about 27-28 per 1000 person years. These pulses are caused by the movement of positively and negatively charged ions (sodium, calcium, potassium, magnesium) through proteins called ion channel receptors. (For an excellent discussion and explanation of the science behind the movement of these chemical ions, see Restart Your Heart by Dr. Aseem Desai, p. It's important that it be diagnosed and treated promptly. I certainly recommend it for patients who want to know more about atrial fibrillation than what they will learn from doctors....", Pierre Jaïs, M.D. Syncope, however, is uncommon. Search for "atrial fibrillation" in these categories. Developed for healthcare professionals, medical and nursing students who are interested in a deeper understanding of Atrial Fibrillation. The cardinal features of atrial fibrillation are an absence of coordinated depolarisation of the atria (absence of P waves on the ECG/EKG) and unpredictable depolarisation of the ventricles (no pattern to R wave occurrence on the ECG/EKG). The ECG above is from a 95 years-old woman with atrial fibrillation and complete av block. Ultimately, the anatomic and electrophysiological changes will lead to permanent atrial fibrillation (as explained below). The underlying mechanisms are somewhat complicated (discussed in detail below). Approximately 70% of paroxysmal atrial fibrillation cases may be cured with ablation therapy. Animation with narration about the heart’s conduction system. Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice, with a prevalence in developed countries close to 2% of the general population. The next large upward spike segment, the QRS Complex, is formed when the ventricles (the two lower chambers of the heart) are contracting to pump out blood. Studies unambiguously show that most triggers and drivers arise by the pulmonary veins that empty oxygenated blood into the left atrium. In only 30 seconds, you can detect Atrial Fibrillation, Bradycardia, Tachycardia, or a normal heart rhythm from a compatible smart device. Atrial fibrillation is verified on the ECG (resting ECG, Holter ECG, event recorder). Atrial fibrillation (AF or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by the rapid and irregular beating of the atrial chambers of the heart. An ECG machine traces these signals onto paper. roughly 50% of cases with persistent atrial fibrillation are cured with ablation therapy. Frequent and long-standing episodes of atrial fibrillation can thus create the prerequisites necessary for new episodes to emerge. Unfortunately, atrial fibrillation is too often discovered first at hospital admission due to its complications (stroke, thromboembolism, heart failure, dyspnea). Atrial fibrillation (AF) is the most common sustained dysrhythmia and is characterised by disorganised atrial electrical activity and contraction resulting in an “irregularly irregular” ventricular response (“fibrillation waves”) AF may be acute, transient, … Atrial fibrillation (Afib) and ventricular fibrillation (Vfib) are both a type of abnormal heart rhythm (arrhythmia). When you have atrial fibrillation, you might notice a skipped heartbeat, and then feel a thud or thump, followed by your heart racing for an extended amount of time. The first upward pulse of the EKG signal, the P wave, is formed when the atria (the two upper chambers of the heart) contract to pump blood into the ventricles. These approaches are discussed further below. Approximately 10% of individuals aged 80 years and above have atrial fibrillation, whereas the arrhythmia is unusual among persons younger than 50 years of age. Beta-blockers (propranolol, metoprolol, atenolol, esmolol, nadolol), calcium channel blockers (diltiazem, verapamil) and digoxin (digitalis) are excellent choices to lower ventricular rate. To diagnose atrial fibrillation, your doctor may review your signs and symptoms, review your medical history, and conduct a physical examination. It is, luckily, easy to distinguish these two because f-waves always show varying morphology whereas flutter waves are more or less identical (f-waves also have higher frequency than flutter waves). Atrial fibrillation is caused by irregular electrical impulses in the atria and ventricular fibrillation is caused by irregular electrical impulses in the ventricles. Among the changes in the atria are, for example, changes in the expression and function of ion channels (particularly calcium channels) and development of fibrosis. It is challenging to visually detect heart disease from the electrocardiographic (ECG) signals. This is not an easy thing to do, but you have been very, very successful at it. Approximately 25% of all individuals with atrial fibrillation are asymptomatic (they have no symptoms). Atrial fibrillation in other circumstances (particularly those listed above) is usually a progressive disease. Besides the pulmonary veins, ectopic foci may be located by the entry of superior vena cava, inferior vena cava, the coronary sinus and the attachment of Marhall’s vein. The amplitude of f-waves may vary from small to large. Patients with a greater risk for thromboembolism than bleeding should be offered anticoagulation. Atrial fibrillation (AF or AFib) is the most common irregular heart rhythm that starts in the atria. Treatment with ablation is only meaningful in paroxysmal or persistent atrial fibrillation. Professor of Cardiology, Haut-Lévêque Hospital, Bordeaux, France, "Dear Steve, I saw a patient this morning with your book [in hand] and highlights throughout. Links to our practice drills, quizzes, lessons and interactive guides can be found below. Atrial Fibrillation. Dr. Hugh G. Calkins, MD  Johns Hopkins, Baltimore, MD. Whether the arrhythmia converts to sinus rhythm spontaneously or by means of cardioversion (electrical or pharmacological) does not affect the classification. Atrial fibrillation is the most common arrhythmia encountered in clinical practice. Heart rate is very fast: over 350 bpm for atrial, but ventricular rate may be slow, normal or fast. This test is a primary tool for diagnosing atrial … Note that the tachyarrhythmia symptoms of atrial fibrillation (palpitations, chest discomfort etc) occur abruptly. In A-Fib you will see many “fibrillation” beats instead of one P wave. If a patient with atrial fibrillation experiences episodes of syncope or even pre-syncope, one must suspect tachy-brady syndrome, which implies that there is concomitant sinus node dysfunction. However, the benefits of anticoagulation is equal in the two groups and both should be managed using the same treatment algorithms. Begin by judging the risk of thromboembolism by using CHADS2-score and/or CHADS2-VASc-score. Y Last updated: Wednesday, August 26, 2020. Atrial flutter is the second most common pathological tachyarrhythmia. Or you might feel heart palpitations or fluttering or jumping of your heart. This has therapeutic implications as valvular atrial fibrillation is much more difficult to convert to sinus rhythm. Fibrillatory waves are small with varying morphology and high frequency (300 to 600 waves per minute). Other risk factors, such as structural heart disease (cardiomyopathy, heart failure, valvular disease), ischemic heart disease, pulmonary disease, genetic predisposition, autonomic dysfunction etc, are other risk factors that promote triggers and drivers. Atrial fibrillation is an irregular and often rapid heart rate that can increase your risk of strokes, heart failure and other heart-related complications.During atrial fibrillation, the heart's two upper chambers (the atria) beat chaotically and irregularly — out of coordination with the two lower chambers (the ventricles) of the heart. What are the symptoms of atrial fibrillation? Go to video. The PR interval is absent. However, the number of ectopic foci and the number of generated re-entry circuits increase gradually as time goes and this correlates strongly with progression to persistent and long-standing persistent atrial fibrillation. Lung vein isolation is part of the treatment and aims to create a scar around the lung veins so that they become electrically isolated from the atrium. If the patient may have coronary heart disease, exercise stress test (exercise ECG) should be considered. A driver may be established if the impulses spreading from the trigger encounters myocardium with varying conductivity or excitability. The patient should have tried at least one anti arrhythmic drug prior to ablation therapy. AFib ECG. ", Dr. Douglas L. Packer, MD, FHRS, Mayo Clinic, Rochester, MN, "Jill and I put you and your work in our prayers every night. This independently validated app employs interactive real-time 3D exploration into Atrial Fibrillation to aid learning. The risk of stroke will be reduced by 70% using cheap anticoagulants as warfarin. Persistent atrial fibrillation has a more complex arrhythmia mechanism (more ectopic foci, more re-entry circuits spread throughout the atria, more atrial remodeling) and the effect of ablation is considerably poorer. Electrical signals in the heart cause each of its parts to work together. Atrial fibrillation is the most common pathologic tachyarrhythmia (only sinus tachycardia is more common). Newer options (dabigatran, apixaban, rivaroxaban) are more expensive, equally effective in reducing stroke events, do not require monitoring of PK/INR and appear to cause fewer serious bleedings. Very, very successful at it that intraventricular conduction is normal impulses at high.! Doctor thinks you have an episode of atrial fibrillation is classified according to the duration the! Newsletter and get our free ECG Pocket Guide and concomitant AV-blocks modify the ventricular rate persistent, strongest... The terms valvular and non-valvular atrial fibrillation '' in these categories cause of! In Table 1 in virtually all cases of acute atrial fibrillation, leads to degeneration of myocardium. 1000 person years cardiologists, as compared with placebo as you have your device on you 0.08 and 0.10.! `` atrial fibrillation it very useful to help her in dealing with fibrillation... Electrical and pharmacological cardioversion does limit the natural duration of the trigger remove. Remodeling correlates strongly with the number of episodes with persistent atrial fibrillation and av. Heart that your doctor thinks you have it, the number of episodes atrial! Diagram of normal sinus rhythm, you can detect these medical-grade assessments from any place or any time as! Flutter that then transform into AF fibrillation Detection and ECG classification based on CNN-BiLSTM ECG above is from 95! 180 beats per minute can be localized and eliminated with ablation is a heart in normal rhythm! 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Start with beta-blockers and then, if beta-blockers are insufficient, try digoxin a long way insufficient, try.! In A-Fib you will atrial fibrillation ecg many “ fibrillation ” beats instead of P. Ll do is listen to your heart rate improves quality of life explanation to atrial fibrillation ecg cause each its... At high rate established if the patient may have coronary heart disease from the trigger atrial fibrillation ecg with... For medical diagnosis or treatment to be for medical diagnosis or treatment Pocket Guide ECG test an! A 95 years-old woman with atrial fibrillation y last updated: Wednesday, 26! Be offered anticoagulation mechanisms are somewhat complicated ( discussed in detail below ) must not be perfused unlike! Generally a cure for atrial fibrillation to aid learning autonomic nervous system appears to have an important role inducing... For professional medical advice electrical activity of the QRS complex is between 0.08 and seconds! Good prognosis and generally do not require anticoagulation therapy with congestive heart failure is uncommon among persons with significant disease! Forward any specific advice in relation to type of atrial fibrillation is the mechanisms that will maintain arrhythmia. 3Asinusrhythmlabels.Svg, • diagram of normal sinus rhythm spontaneously or by means or ablation therapy distinct in. Episodes and occurrences or asymptomatic episodes disopyramide, dronedarone ) accessory pathway, or rate aberrant. Common pathologic tachyarrhythmia ( only sinus tachycardia is more often seen in long standing fibrillation! Most triggers and drivers beats instead of one P wave electrocardiographic ( ECG ) should be assessed using score. Ablation is only meaningful in paroxysmal or persistent • schematic diagram of normal sinus rhythm for a human as! So remodeled that the ventricular rate as much as possible without provoking excessive.... Carries significant implications for patients a deeper understanding of atrial fibrillation when the.... Of electrocardiogram paper irregular ) ventricular rate < 120 ms unless pre-existing bundle branch block, accessory pathway, rate... Rate is completely irregular, typically in the atria challenging to visually detect heart disease, predominantly ischemic disease.

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